Status Quo of Microreactor Industry at Home and Abroad

In the early 1990s, the research on micro-chemical technology started abroad. The United States, Germany, Britain, France, Japan and other developed countries have successively carried out research on microchemical engineering and technology. According to incomplete statistics, there are currently more than 50 suppliers of micro-chemical technology and equipment in the world, of which Europe accounts for about 60%. It can be seen from Table 1 that each microreactor system has its own characteristics and represents the current advanced level and development direction of microreactor design and manufacture.

The microreactor module of Ehrfeld Company in Germany can be easily disassembled and cleaned.
The Mini-lab micro-reaction system of Corning Corporation of the United States is a highly integrated modular device, including functional modules such as mixing, reaction, and heat exchange. All modules are made of glass.
The Siprocess microreactor system from Siemens is an integrated modular system, which is characterized by the installation of electronic systems for measurement and control in each module, making it easier and more precise to control the reaction process.
An electrochemical microreactor for the synthesis of methoxybenzaldehyde from p-methoxybenzylmethane was pioneered by the Mainz Institute in Germany.
The Massachusetts Institute of Technology has developed a micro-packed reactor for gas-liquid-solid three-phase catalytic reaction.
Hull University in the UK designed a T-shaped liquid-liquid phase microreactor, the biggest feature of which is the use of electroosmosis to transport fluids.
The T-shaped thin-walled microreactor designed and manufactured by MIT is a representative gas-phase microreactor.
Domestic research on microreactors has been carried out for more than ten years. It has developed rapidly in the fields of design and manufacture of microreactors, exploration of micro-mixing principles, gas-phase reactions, liquid-phase reactions, and nanoparticle preparation, and has achieved remarkable results. At present, the main research institutions of micro-reaction technology are Dalian University of Technology, University of Science and Technology of China, East China University of Science and Technology, Beijing University of Chemical Technology, etc.
The Institute of Chemical Machinery, East China University of Science and Technology produced a plate for a methanol steam reforming hydrogen production microreactor.
The University of Science and Technology of China developed a ceramic microreactor by the sintering method and carried out the experiment of the ethanol water-gas reforming microreactor, and obtained gratifying results.
Beijing University of Chemical Technology has researched and prepared a soft-shell microreactor for the current macroscopic reaction system that cannot effectively treat ultra-low concentration pollutants. new method.

Dalian University of Technology introduced zeolite and zeolite membrane into the microreactor, which can realize the combination of multiple advantages of zeolite catalysis, membrane catalysis and microreaction technology.
In addition to universities and research institutes, a number of excellent microreactor manufacturers have emerged in the domestic market. Taking Hangzhou Hangzhou Micro-control Energy Conservation Co., Ltd. as an example, relying on various R&D teams in cooperation with well-known domestic universities, Zhejiang University, Tsinghua University, China Jiliang University, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, and Tianjin University, we focus on the development of chemical processes and industrial continuity. Equipment system, successfully developed and produced the third-generation integrated micro-channel heat exchanger products and micro-environment system equipment, realizing the localization of industrialized micro-reactors, integrated catalyst-supported micro-channel reactors, integrated micro-channel mixers, integrated micro-channel reactors It is not uncommon for channel reaction systems to be used in industrial cases. Hangzhou Shenshi’s development of localized microreactors is not only reflected in equipment, but as a new third board listed company, after accumulating strong advantages in the field of equipment, it has expanded to the field of military products. It is worth looking forward to the future performance of Hangzhou Shenshi in the microreactor industry.
Relying on a strong process R&D and fluid simulation team, combined with advanced machining capabilities, Himile can provide customers with the development and design of a complete set of micro-reaction system engineering.
Microwell Technology, which was born out of Himile, creatively developed RTB microreactor with rectangular channel disc cross mixing channel based on the precision processing equipment based on fluid mechanics design.
From the results, the microreactor has indeed promoted a large number of pharmaceutical and chemical enterprises to achieve a comprehensive upgrade of process technology.
In 2011, Sinopec Nanhua Group Research Institute introduced the high-throughput-microchannel continuous flow reactor from Corning Corporation of the United States, and successfully developed new processes for nitration of chlorobenzene and special rubber additives. Jiangsu Yangnong Chemical Pesticide adopts Hangzhou Shenshi integrated microchannel reactor device, which not only occupies less space, but also increases the product yield by 6-8%, saving more than 1 million energy costs per year.
In recent years, systematic research on microreactors has been carried out at home and abroad, and breakthroughs have been made in key technologies such as the design, manufacture, integration and amplification of microreactors. However, in order to truly replace traditional reactors for actual production, microreactors still need to solve some problems.